Dmitry Lim. Curriculum Vitae
PERSONAL DATA
Born Kazan, Russia, 29/10/1968
Work address Venetian Institute of Molecular Medicine (VIMM), Via Orus 2, 35129, Padova, Italy

Tel.
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Fax.
E-mail
Web
+39 0497923241
+39 0498276135
+39 0498276125
dlim@bio.unipd.it
www.dmlim.net

CURRENT POSITION
January 2007 - present Postdoctoral fellow. Marie Curie Fellowship granted in frame of the NeuroNE program. Laboratory of Prof. Ernesto Carafoli, Venetian Institute of Molecular Medicine (VIMM), Padova.

POSITIONS HELD
2004 - 2006 Postdoctoral fellow. Department of Biochemistry, University of Padova.

EDUCATION
1999 - 2003 PhD program of The Open University of London in Physiology and Cell Biology at the Stazione Zoologica di Napoli (SZN) "Anton Dohrn". The title of the PhD thesis: Calcium signals mediated by InsP3 and NAADP during maturation and fertilization of satrfish oocytes.
1995 - 1999 The Moscow State University (MSU), Russia. Degree in physiology with Honor. The title of the diploma work: The role of heat shock proteins in the pattern of the macrophage migration in vivo.
1992 - 1993 The Novokuybishevsk School of Nursing, Russia. Degree in Nursing with Honor.

TEACHING AND STUDENTS SUPERVISION
2008

Course "Calcium and disease" given in frame of the Ph.D. program of the Department of Biochemistry at the University of Padova.

2004-2008

Supervision of a number of students in experimental work towards their Master degree in Pharmaceutical Chemistry and Technology, Sanitary Biology, and Experimental Biotechnology.

TALKS and SEMINARS
October 2005

Oral presentation: "Regulation of neuronal calcium homeostatis by DREAM". VIMM symposium. Monteortone, Italia.

November 2005

Seminar: "Where and how we measure calcium". CNB. Madrid, Spain.

October 2007

Oral presentation: "Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington's disease". 14th International Symposium on Calcium-Binding Proteins and Calcium Function in Health and Disease. La Palma, Canary Islands, Spain.

October 2007

Oral presentation: "Mitochondrial defects and calcium signaling dysfunction in a striatal cell model of Huntington's disease". NeuroNE Workshop on Neuronal Calcium in Health and Disease. La Palma, Canary Islands, Spain.

November 2007

Oral presentation: "Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington's disease". VIMM symposium. Marostica, Italia.

October 2008

Seminar: "Biosensors for intracellular calcium: Applications from oocyte maturation to neurodegeneration". Department of Pharmacology, University of Piemonte Orientale. Novara, Italy.

November 2008

Oral presentation: "Interplay of Ca2+-binding protein DREAM with Presenilin in Neuronal Ca2+ Signaling: possible role in Alzheimer's disease". VIMM symposium. Bassano del Grappa, Italy


KEY REFERENCES     (Link to full list of publications)
7 Lim D, Fedrizzi L, Tartari M, Zuccato C, Cattaneo E, Brini M, Carafoli E. (2007) Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington′s disease. J Biol Chem. published online ahead of print December 21, 2007. PDF 1m
6 Ficarella R, Di Leva F, Bortolozzi M, Ortolano S, Donaudy F, Petrillo M, Melchionda S, Lelli A, Domi T, Fedrizzi L, Lim D, Shull GE, Gasparini P, Brini M, Mammano F, Carafoli E. (2007) A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness. Proc Natl Acad Sci U S A. 104:1516-1521. PDF 1.5m
5 Moccia F, Nusco GA, Lim D, Kyozuka K, Santella L. (2006) NAADP and InsP3 play distinct roles at fertilization in starfish oocytes. Dev Biol. 294:24-38. PDF 870k
4 Santella L, Lim D, Moccia F. (2004). Calcium and fertilization: the beginning of life. Trends Biochem. Sci. 29, 400-408. PDF 1m
3 Moccia F, Lim D, Kyozuka K, Santella L. (2004). NAADP triggers the fertilization potential in starfish oocytes. Cell Calcium. 36, 515-524. PDF 350k
2 Lim, D., Ercolano, E., Kyozuka, K., Nusco, G.A., Moccia, F., Lange, K. and Santella, L. (2003). The M-phase promoting factor modulates the sensitivity of the Ca2+ stores to inositol 1,4,5-trisphosphate via the actin cytoskeleton. J Biol Chem. 278, 42505-42514. PDF 810k
1 Lim, D., Kyozuka, K., Gragnaniello, G., Carafoli, E. and Santella, L. (2001). NAADP+ initiates the Ca2+ response during fertilization of starfish oocytes. FASEB J. 15, 2257-2267 PDF 750k