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| PERSONAL DATA |
| Born |
Kazan, Russia, 29/10/1968 |
| Work address |
Venetian Institute of Molecular Medicine (VIMM), Via Orus 2, 35129, Padova, Italy
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Tel.
Tel.
Fax.
E-mail
Web |
+39 0497923241
+39 0498276135
+39 0498276125
dlim@bio.unipd.it
www.dmlim.net
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| CURRENT POSITION |
| January 2007 - present |
Postdoctoral fellow. Marie Curie Fellowship granted in frame of the NeuroNE program. Laboratory of Prof. Ernesto Carafoli,
Venetian Institute of Molecular Medicine (VIMM), Padova.
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| POSITIONS HELD |
| 2004 - 2006 |
Postdoctoral fellow.
Department of Biochemistry, University of Padova.
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| EDUCATION |
| 1999 - 2003 |
PhD program of The Open University of London in Physiology and Cell Biology
at the Stazione Zoologica di Napoli (SZN) "Anton Dohrn". The title of the
PhD thesis: Calcium signals mediated by InsP3 and NAADP
during maturation and fertilization of satrfish oocytes. |
| 1995 - 1999 |
The Moscow State University (MSU), Russia. Degree in physiology with Honor.
The title of the diploma work: The role of heat shock proteins in the
pattern of the macrophage migration in vivo. |
| 1992 - 1993 |
The Novokuybishevsk School of Nursing, Russia. Degree in Nursing with Honor.
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| TEACHING AND STUDENTS SUPERVISION |
| 2008 |
Course "Calcium and disease" given in frame of the Ph.D. program of the Department of Biochemistry at the University of Padova.
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| 2004-2008 |
Supervision of a number of students in experimental work towards their Master degree in Pharmaceutical Chemistry and Technology, Sanitary Biology, and Experimental Biotechnology.
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| TALKS and SEMINARS |
| October 2005 |
Oral presentation: "Regulation of neuronal calcium homeostatis by DREAM". VIMM symposium. Monteortone, Italia.
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| November 2005 |
Seminar: "Where and how we measure calcium". CNB. Madrid, Spain.
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| October 2007 |
Oral presentation: "Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington's disease".
14th International Symposium on Calcium-Binding Proteins and Calcium Function in Health and Disease.
La Palma, Canary Islands, Spain.
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| October 2007 |
Oral presentation: "Mitochondrial defects and calcium signaling dysfunction in a striatal cell model of
Huntington's disease". NeuroNE Workshop on Neuronal Calcium in Health and Disease.
La Palma, Canary Islands, Spain.
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| November 2007 |
Oral presentation: "Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington's disease".
VIMM symposium. Marostica, Italia.
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| October 2008 |
Seminar: "Biosensors for intracellular calcium: Applications from oocyte maturation to neurodegeneration".
Department of Pharmacology, University of Piemonte Orientale. Novara, Italy.
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| November 2008 |
Oral presentation: "Interplay of Ca2+-binding protein DREAM with Presenilin in Neuronal Ca2+ Signaling:
possible role in Alzheimer's disease". VIMM symposium. Bassano del Grappa, Italy
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| KEY REFERENCES (Link to full list of publications) |
| 7 |
Lim D, Fedrizzi L, Tartari M, Zuccato C, Cattaneo E, Brini M, Carafoli E. (2007)
Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington′s disease.
J Biol Chem. published online ahead of print December 21, 2007.
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PDF 1m |
| 6 |
Ficarella R, Di Leva F, Bortolozzi M, Ortolano S, Donaudy F, Petrillo M,
Melchionda S, Lelli A, Domi T, Fedrizzi L, Lim D, Shull GE, Gasparini P, Brini M,
Mammano F, Carafoli E. (2007)
A functional study of plasma-membrane calcium-pump isoform 2 mutants causing
digenic deafness.
Proc Natl Acad Sci U S A. 104:1516-1521.
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PDF 1.5m |
| 5 |
Moccia F, Nusco GA, Lim D, Kyozuka K, Santella L. (2006)
NAADP and InsP3 play distinct roles at fertilization in starfish oocytes.
Dev Biol. 294:24-38.
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PDF 870k |
| 4 |
Santella L, Lim D, Moccia F. (2004). Calcium and fertilization: the beginning of life.
Trends Biochem. Sci. 29, 400-408.
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PDF 1m |
| 3 |
Moccia F, Lim D, Kyozuka K, Santella L. (2004). NAADP triggers the fertilization potential in starfish oocytes.
Cell Calcium. 36, 515-524.
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PDF 350k |
| 2 |
Lim, D., Ercolano, E., Kyozuka, K., Nusco, G.A., Moccia, F., Lange, K. and Santella, L. (2003). The M-phase promoting factor modulates the sensitivity of the Ca2+ stores to inositol 1,4,5-trisphosphate via the actin cytoskeleton.
J Biol Chem. 278, 42505-42514.
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PDF 810k |
| 1 |
Lim, D., Kyozuka, K., Gragnaniello, G., Carafoli, E. and Santella, L. (2001). NAADP+ initiates the Ca2+ response during fertilization of starfish oocytes.
FASEB J. 15, 2257-2267
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PDF 750k |
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